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The following is a list of some of the most recent publications from our faculty. For a complete list of publications of individual faculty members go to faculty and click on the name to get to the personal webpages.


Maureen Ajuebor

Ajuebor MN

Role of NKT cells in the digestive system. Invariant NKT Cells and Liver Diseases:  Is there strength in numbers?pdf-fileabstract

Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G651-6. Epub 2007 Jul 12. Review

 
 

Ajuebor MN, Wondimu Z, Hogaboam CM, Le T, Proudfoot AE, Swain MG

CCR5 Deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis

Am J Pathol. 2007 June;170(6):1975-88

 
 

Ajuebor MN, Carey JA, Swain MG.
CCR5 in T cell-mediated liver diseases: what's going on?abstract
J Immunol. 2006 Aug 15;177(4):2039-45. Review.

 
 


Jonathan Steven Alexander
 
 

Benoit C, Gu Y, Zhang Y, Alexander JS, Wang Y.

Contractility of Placental Vascular Smooth Muscle Cells in Response to Stimuli Produced by the Placenta: Roles of ACE vs. Non-ACE and AT1 vs. AT2 in Placental Vessel Cells.

Placenta. 2008 Jun;29(6):503-509. Epub 2008 Apr 15.abstract

 

 

Minagar A, Commins D, Alexander JS, Hoque R, Chiappelli F, Singer EJ, Nikbin B, Shapshak P.

NeuroAIDS: characteristics and diagnosis of the neurological complications of AIDS.

Mol Diagn Ther. 2008;12(1):25-43.abstract

 
 

Carpenter A, Rassam A, Jennings MH, Robinson-Jackson S, Alexander JS, Erkuran-Yilmaz C.

Effects of ammonium tetrathiomolybdate, an oncolytic/angiolytic drug on the viability and proliferation of endothelial and tumor cells.

Inflamm Res. 2007 Dec;56(12):515-9.pdf-fileabstract

 
 

Minagar A, Alexander JS, Schwendimann RN, Kelley RE, Gonzalez-Toledo E, Jimenez JJ, Mauro L, Jy W, Smith SJ.

Combination therapy with interferon Beta-1a and doxycycline in multiple sclerosis: an open-label trial.

Arch Neurol. 2008 Feb;65(2):199-204. Epub 2007 Dec 10.pdf-fileabstract

 
 

Alexander JS, Mathis JM, Pruitt K.

Interaction of microsatellite instability and loss of heterozygosity in adenocarcinoma: multiple markers in adenocarcinoma: an introduction to 'Genetic changes in Slovenian patients with gastric adenocarcinoma evaluated in terms of microsatellite DNA'.

Eur J Gastroenterol Hepatol. 2007 Dec;19(12):1038-40.pdf-fileabstract

 
 

Alexander JS, Allis DG, Teng W, Ruhlandt-Senge K.

Alkali metal diphenylmethanides: synthetic, computational and structural studies.

Chemistry. 2007;13(35):9899-911.

abstract

 
 
 
Tak Yee Aw
 

Circu ML, Rodriguez C, Maloney R, Moyer MP, Aw TY.

Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis.

Free Radic Biol Med. 2008 Mar 1;44(5):768-78. Epub 2007 Sep 25.pdf-fileabstract

 

Okouchi M, Ekshyyan O, Maracine M, Aw TY

Neuronal apoptosis in neurodegeneration

Antioxid Redox Signal. 2007 Aug;9(8):1059-96pdf-fileabstract

 

Okouchi M, Okayama N, Alexander JS, Aw TY

NRF2-dependent  glutamate-L-cysteine ligase catalytic  subunit expression mediates insulin protection against hyperglycemia-induced brain endothelial cell apoptosis

Curr Neurovasc Res.  2006 Nov;3(4):249-61abstract

 
 
 
D. Neil Granger
 
 

Tailor A, Wood KC, Wallace JL, Specian RD, Granger DN.

Roles of platelet and endothelial cell COX-1 in hypercholesterolemia-induced microvascular dysfunction.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3636-42. Epub 2007 Oct 12

pdf-file
   

Gavins F, Yilmaz G, Granger DN.

The evolving paradigm for blood cell-endothelial cell interactions in the cerebral microcirculation.

Microcirculation. 2007 Sep-Oct;14(7):667-81. Review.

 
 

Arumugam TV, Tang SC, Lathia JD, Cheng A, Mughal MR, Chigurupati S, Magnus T, Chan SL, Jo DG Ouyang X, Fairlie DP, Granger DN, Vortmeyer A, Basta M, Mattson MP

Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death.

Proc Natl Acad Sci USA. 2007 Aug 28;104(35):14104-9. Epub 2007 Aug. 21pdf-fileabstract

 
 

Wood KC, Granger DN

Sickle cell disease:  role of reactive oxygen and nitrogen metabolites

Clin Exp Pharmacol Physiol. 2007 Sep;34(9):926-32pdf-fileabstract

 
 

Singer G, Granger DN.

Inflammatory responses underlying the microvascular dysfunction associated with obesity and insulin resistance.

Microcirculation. 2007 Jun-Jul;14(4-5):375-87. Review.abstract

 
 

Anthoni C, Russell J, Wood KC, Stokes KY, Vowinkel T, Kirchhofer D, Granger DN.

Tissue factor: a mediator of inflammatory cell recruitment, tissue injury, and thrombus formation in experimental colitis.

J Exp Med. 2007 Jul 9;204(7):1595-601. Epub 2007 Jun 11.pdf-fileabstract

 
Matthew Grisham

 

Bryan NS, Grisham MB

Methods to detect nitric oxide and its metabolites in biological samples.

Free Radic Biol Med. 2007 Sep 1;43(5):645-57. Epub 2007 Apr. 29pdf-fileabstract

 
 
abstract pdf-file

Urakami H, Abe Y, Grisham MB.

Role of reactive metabolites of oxygen and nitrogen in partial liver transplantation:  lessons learned from reduced-size liver ischaemia and reperfusion injury.

Clin Exp Pharmacol Physiol. 2007 Sep;34(9):912-9.

 
 

Chidlow JH Jr, Shukla D, Grisham MB, Kevil CG.

Pathogenic angiogenesis in IBD and experimental colitis: new ideas and therapeutic avenues.

Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G5-G18. Epub 2007 Apr 26. Review.pdf-file

abstract

 
 
 
Norman R. Harris  
 

Wright WS, Harris NR.

Ozagrel attenuates early streptozotocin-induced constriction of arterioles in the mouse retina.

Exp Eye Res. 2008 Jan 9; [Epub ahead of print]abstractpdf-file

 
 

Harris NR, Specian RD, Carter PR, Morgan GA.

Contrasting effects of pseudoephedrine and papaverine in dextran sodium sulfate-induced colitis.

Inflamm Bowel Dis. 2008 Mar;14(3):318-23.

pdf-fileabstract

 
 

Langford MP, Redens TB, Harris NR, Lee S, Jain SK, Reddy S, McVie R.

Plasma levels of cell-free apoptotic DNA ladders and gamma-glutamyltranspeptidase (GGT) in diabetic children.

Exp Biol Med (Maywood). 2007 Oct;232(9):1160-9.

pdf-fileabstract

 
 
 
Lynn Harrison
 

Malyarchuk S, Wright D, Castore R, Klepper E, Weiss B, Doherty AJ, Harrison L.

Expression of mycobacterium tuberculosis Ku and Ligase D in Escherichia coli results in RecA and RecB-independent DNA end-joining at regions of micromology.

DNA Repair (Amst). 2007 Jun 6; [Epub ahead of print]pdf-fileabstract

 
 
abstract pdf-file

Harrison L, Brame KL, Geltz LE, Landry AM.

Closely opposed apurinic/apyrimidinic sites are converted to double strand breaks in Escherichia coli even in the absence of exonuclease III, endonuclease IV, nucleotide excision repair and AP lyase cleavage. DNA Repair (Amst). 2006 Mar 7;5(3):324-35. Epub 2005 Dec 6.

 
 
 
Yijun Jin
 
abstract pdf-file

Jin Y, Blue EK, Gallagher PJ.

Control of death-associated protein kinase (DAPK) activity by phosphorylation and proteasomal degradation.

J Biol Chem. 2006 Dec 22;281(51):39033-40. Epub 2006 Oct 20.

 

Kevin Pruitt
 
abstract pdf-file

Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, Herman JG, Baylin SB.

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet. 2007 Feb;39(2):237-42. Epub 2007 Jan 9.

 
 
abstract

Zinn RL, Pruitt K, Eguchi S, Baylin SB, Herman JG.pdf-file

hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site. Cancer Res. 2007 Jan 1;67(1):194-201.

 
 
abstract

Pruitt K, Zinn RL, Ohm JE, McGarvey KM, Kang SH, Watkins DN, Herman JG, Baylin SB.pdf-file

Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet. 2006 Mar;2(3):e40. Epub 2006 Mar 31.

 
 
 
Chantal Rivera
 
 

Rivera CA, Granger DN, Singer G.

Reply to: Hepatic microvascular dysfunction and endotoxemia in sepsis.

J Hepatol. 2008 Apr;48(4):677. Epub 2008 Jan 28. No abstract available.pdf-file

 
 

Singer G, Houghton J, Rivera CA, Anthoni C, Granger DN.

Role of LPS in the hepatic microvascular dysfunction elicited by cecal ligation and puncture in mice.

J Hepatol. 2007 Dec;47(6):799-806. Epub 2007 Sep 24.pdf-fileabstract

 
 

Rivera CA, Adegboyega P, van Rooijen N, Tagalicud A, Allman M, Wallace M.

Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis.

J Hepatol. 2007 Oct;47(4):571-9. Epub 2007 Jun 8.pdf-file

abstract

 
 

Quiros-Tejeira RE, Rivera CA, Ziba TT, Mehta N, Smith CW, Butte NF. Risk for nonalcoholic fatty liver disease in Hispanic youth with BMI > or =95th percentile.

J Pediatr Gastroenterol Nutr. 2007 Feb;44(2):228-36.

abstract
 
Robert Specian
 
abstract

Singer G, Urakami H, Specian RD, Stokes KY, Granger DN.    

Platelet recruitment in the murine hepatic microvasculature during experimental sepsis: role of neutrophils.

Microcirculation. 2006 Mar;13(2):89-97.

 
 
 
Karen Stokes
 

Wolfort RM, Stokes KY, Granger DN.

CD4+ T-lymphocytes mediate hypercholesterolemia-induced endothelial dysfunction via a NAD(P)H oxidase-dependent mechanism.

Am J Physiol Heart Circ Physiol. 2008 Apr 11. [Epub ahead of print]abstractpdf-file

 
   
 
   
abstractpdf-file

Terao S, Yilmaz G, Stokes KY, Ishikawa M, Kawase T, Granger DN.

Inflammatory and Injury Responses to Ischemic Stroke in Obese Mice.

Stroke. 2008 Jan 31; [Epub ahead of print]

 
 
 
pdf-fileabstract

Singer G, Stokes KY, Granger DN.

Hepatic microcirculation in murine sepsis: role of lymphocytes.

Pediatr Surg Int. 2008 Jan;24(1):13-20.

 
 
abstractpdf-file

Vowinkel T, Wood KC, Stokes KY, Russell J, Tailor A, Anthoni C, Senninger N, Krieglstein CF, Granger DN.

Mechanisms of platelet and leukocyte recruitment in experimental colitis.

Am J Physiol Gastrointest Liver Physiol. 2007 Nov;293(5):G1054-60. Epub 2007 Sep 20.
 
 
abstract

Stokes KY, Gurwara S, Granger DN.

T-cell derived interferon-gamma contributes to arteriolar dysfunction during acute hypercholesterolemia.

Arterioscler Thromb Vasc Biol. 2007 Sep;27(9):1998-2004. Epub 2007 Jun 21.pdf-file

 
 

Stokes KY, Russell JM, Jennings MH, Alexander JS, Granger DN.

Platelet-associated NAD(P)H oxidase contributes to the thrombogenic phenotype induced by hypercholesterolemia.

Free Radic Biol Med. 2007 Jul 1;43(1):22-30. Epub 2007 Mar 12.pdf-fileabstract

 
Tomas Welbourne  
 

Friday E, Oliver R 3rd, Welbourne T, Turturro F.

Role of epidermal growth factor receptor (EGFR)-signaling versus cellular acidosis via Na+/H+ exchanger1(NHE1)-inhibition in troglitazone-induced growth arrest of breast cancer-derived cells MCF-7.

Cell Physiol Biochem. 2007;20(6):751-62.pdf-fileabstract

 
 

Turturro F, Friday E, Welbourne T.

Hyperglycemia regulates thioredoxin-ROS activity through induction of thioredoxin-interacting protein (TXNIP) in metastatic breast cancer-derived cells MDA-MB-231.

BMC Cancer. 2007 Jun 7;7:96.pdf-fileabstract

 
 

Turturro F, Driscoll M, Friday E, Welbourne T.

ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: does it matter for oncogenesis?

Haematologica. 2007 May;92(5):706-7.pdf-fileabstract

 
 

Turturro F, Lawson M, Friday E, Welbourne T.

Targeting the Na(+)/H(+) exchanger: An old concept with new perspectives in the treatment of hematological malignancies. Leuk Res. 2006 Dec 13; [Epub ahead of print]abstract

 


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